Centrosomal protein 95 (CEP95)

Centrosomal protein 95 (CEP95) is a coiled-coil domain–containing protein localized at the centrosome and spindle poles, essential for proper centrosome organization and function during cell division[1][3][5]. It is implicated in diverse biological processes, including tumor progression (serving as a potential hub gene in cancer co-expression networks, notably in lung adenocarcinoma), regulation of telomere length (in pathways affecting cellular aging), and human growth regulation (identified in genetic studies associated with height)[1]. While CEP95 is not an established therapeutic drug target, its altered expression or mutation has been linked to multiple disease phenotypes and cellular processes. Key points: - CEP95 is a centrosomal structural protein, not functioning as a receptor, enzyme, or transporter[1][5]. - It serves housekeeping roles in centrosome-associated processes and is emerging for its potential significance in oncology and genetics[1]. - There are currently no drugs known to directly target CEP95, and no formal safety concerns or mechanisms of action for therapeutic intervention are established. Note: CEP95 is not a receptor, enzyme, or transporter, and is not currently considered a direct therapeutic target, although its roles in cancer and cell cycle regulation make it of significant research interest[1][5].

Other names

Centrosomal protein of 95 kDaCEP95CCDC45CEP45DKFZp667E1824Coiled-coil domain-containing protein 45centrosomal protein 95 kDacoiled-coil domain containing 45