Target intelligence / Profile preview

CEP152 antisense RNA 1 (CEP152-AS1)

Target
CEP152-AS1
Molecular classification
Other (long non-coding RNA, lncRNA)
01

Overview

CEP152 antisense RNA 1 (CEP152-AS1) is a long non-coding RNA gene transcribed from the genomic locus antisense to the coding gene CEP152, which encodes a centrosomal protein involved in centriole duplication. The biological function, mechanistic roles, and disease relevance of CEP152-AS1 have not been well-characterized in the scientific literature. Unlike the protein-coding CEP152 gene, for which there are established roles in cell division and disease, notably primary microcephaly, there are currently no clinical, therapeutic, or biomarker applications attributed to the antisense CEP152-AS1 transcript. No interacting drugs, disease roles, or established biological functions have been reported for this lncRNA. It does not fall into established classes such as receptor, enzyme, transporter, ion channel, or transcription factor, and is not considered a validated therapeutic target.

Other names
lncCEP152-AS1long non-coding RNA CEP152-AS1
02

Biological functions

Other (Potential roles in gene expression regulation at the RNA level; little experimentally validated functional annotation available for CEP152-AS1 specifically)
03

Disease associations

Other (No validated disease association or established role in pathology reported for CEP152-AS1 itself; its parental gene, CEP152, is involved in microcephaly, but this is not documented for the lncRNA antisense)

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