Cerebral Vasculature (N/A)

The cerebral vasculature is the network of blood vessels (arteries, arterioles, capillaries, venules, and veins) responsible for supplying oxygen and nutrients to the brain and removing waste products. It plays a critical role in maintaining brain homeostasis and its dysfunction is implicated in various neurological disorders. It is an anatomical target comprising all vascular elements supplying/draining brain tissue. The cerebral vasculature features unique structural adaptations compared with systemic vasculature, critical for supporting CNS function under high metabolic demand while maintaining strict homeostatic control over fluid exchange across vessel walls.

Other names

Brain vasculatureCerebral blood vesselsNeurovasculature

Varies depending on the specific drug and target within the cerebral vasculature, including vasodilation, reduction of platelet aggregation, blood pressure control, cholesterol reduction and inflammation modulation.