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Cervical Glandular Epithelium

Molecular classification: Epithelial Tissue

Overview

The cervical glandular epithelium, also known as the columnar or endocervical epithelium, is a specialized epithelial tissue lining the endocervical canal of the uterine cervix. It consists of a single layer of tall, columnar cells with dark-staining nuclei located near the basement membrane. It secretes mucus and other fluids that play roles in fertility by facilitating sperm passage and providing protection against pathogens. The transformation zone—where glandular meets squamous epithelium—is clinically significant as it is prone to metaplasia and neoplastic transformation.

Other names: Columnar EpitheliumEndocervical Epithelium

Biological functions

Mucus secretionSperm passage facilitationPathogen protectionPhysical barrierImmunological barrier

Disease associations

Cervical cancerHPV infection

Safety considerations

Transformation zone prone to metaplasia and neoplastic transformation

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