Target intelligence / Profile preview

Cervical plexus sensory branch (None)

Target
None
Molecular classification
Other — peripheral nerve branches
01

Overview

The cervical plexus sensory branches are four cutaneous nerves originating from the cervical plexus, formed by the anterior rami of spinal nerves C2–C4. These branches—lesser occipital nerve (C2), great auricular nerve (C2–C3), transverse cervical nerve (C2–C3), and supraclavicular nerves (C3–C4)—emerge near the posterior border of the sternocleidomastoid muscle at the "nerve point of the neck." They provide sensory innervation to the skin of the neck, parts of the head (behind and around the ear), upper chest, and shoulder regions. The branches have clinical relevance for surface anesthesia in procedures such as carotid endarterectomy or clavicle surgery, targeted by local anesthetic nerve blocks. In summary, "cervical plexus sensory branches" represents an anatomical nerve group, not a molecular target or receptor, and is best described in anatomical rather than molecular or pharmacological terms.

Other names
Cervical plexus cutaneous branchesSensory branches of cervical plexussuperficial branches of cervical plexusnerve point of the neck (clinical landmark)
02

Mechanism of action

For interacting drugs: Blockade of action potential propagation in nerve fibers via inhibition of voltage-gated sodium channels

03

Biological functions

Sensory innervation to skin of anterolateral neckSensory innervation to superior thorax (superolateral thoracic wall)Sensory innervation to scalp between auricle and external occipital protuberance
04

Disease associations

Indirect relevance in regional anesthesia (nerve block)nerve injury syndromesneuropathic painsensory neuropathies
05

Safety considerations

Local anesthetic toxicityInadvertent phrenic nerve block (risk of diaphragmatic paralysis)Nerve injuryVascular puncture
06

Interacting drugs

lidocaine

1 more in the full profile.

07

Biomarkers

None

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