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The cervical plexus sensory branches are four cutaneous nerves originating from the cervical plexus, formed by the anterior rami of spinal nerves C2–C4. These branches—lesser occipital nerve (C2), great auricular nerve (C2–C3), transverse cervical nerve (C2–C3), and supraclavicular nerves (C3–C4)—emerge near the posterior border of the sternocleidomastoid muscle at the "nerve point of the neck." They provide sensory innervation to the skin of the neck, parts of the head (behind and around the ear), upper chest, and shoulder regions. The branches have clinical relevance for surface anesthesia in procedures such as carotid endarterectomy or clavicle surgery, targeted by local anesthetic nerve blocks. In summary, "cervical plexus sensory branches" represents an anatomical nerve group, not a molecular target or receptor, and is best described in anatomical rather than molecular or pharmacological terms.
For interacting drugs: Blockade of action potential propagation in nerve fibers via inhibition of voltage-gated sodium channels
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