CFAP20 domain containing protein (CFAP20DC)

CFAP20 domain containing protein (CFAP20DC), also known as C3orf67, is a poorly characterized human protein encoded by the gene C3orf67[1]. The primary sequence consists of 759 amino acids, with multiple isoforms described[1]. While post-translational modifications (including sumoylation, glycosylation, and phosphorylation) are predicted, neither the protein’s precise molecular function nor its biological pathways are known[1]. There is no evidence that this protein is a classic receptor, enzyme, transporter, or other therapeutically relevant target, nor are there reported disease associations or known drug interactions[1][8]. The molecular structure includes putative domains such as DUF667, but functional studies are lacking[1].\n\nNote: The abbreviation “CFAP20DC” can be confused with the much better-studied gene/protein CFAP20 (Cilia- and flagella-associated protein 20), which is a structural cilia protein conserved across species and involved in cilia function and retinal disease in mutants[2][4][5][6][7]. This entry, however, refers specifically to "CFAP20 domain containing," meaning it is distinct from "CFAP20" itself; thus, the entry does not correspond to a recognized therapeutic target or well-characterized receptor, enzyme, or transporter[1][8].

Other names

CFAP20DCC3orf67Chromosome 3 open reading frame 67FLJ42117FLJ42930Uncharacterized protein C3orf67