Chaperonin containing TCP1 subunit 6 pseudogene 2 (CCT6P2)

Chaperonin containing TCP1 subunit 6 pseudogene 2 (CCT6P2) is a pseudogene and does not code for a functional protein product[1][2][3]. It is related by sequence homology to genes encoding subunits of the Chaperonin containing TCP1 (CCT), also known as the TCP1 ring complex (TRiC), which is a molecular chaperone complex involved in folding newly synthesized proteins such as actin and tubulin[5][6][7]. However, unlike functional subunits like CCT6A or CCT6B, CCT6P2 represents a non-functional remnant—a product of duplicated or inactivated gene copy that has lost protein-coding ability and is not known to have biological functions, disease associations, or value as a therapeutic target[1][2][3]. No drugs are known to interact with this pseudogene, and it is not used as a biomarker or subject to safety concerns. Key clarifications: - CCT6P2 is incorrectly listed as a therapeutic or direct biological target because it is a pseudogene and not a functional chaperonin subunit[1][2][3]. - The functional CCT6A and CCT6B genes have roles in protein folding and disease, but these do not apply to CCT6P2[4][5][6][7].

Other names

CCT6-1Pchaperonin containing TCP1, subunit 6 (zeta) pseudogene 2CCT6P2