Charcot-Leyden crystal protein pseudogene 2 (CLCP2)

Charcot-Leyden crystal protein pseudogene 2 (CLCP2, also known as LGALS10P1) is a non-functional genomic sequence that shares similarity to the gene encoding Charcot-Leyden crystal protein (galectin-10/LGALS10) but does not produce a functional protein. While some pseudogenes are transcribed and may play regulatory roles (such as through RNA decoy mechanisms affecting gene expression), there is no evidence that CLCP2 has such function or that it serves as a receptor, enzyme, or disease target. The functional Charcot-Leyden crystal protein (galectin-10) is highly expressed in human eosinophils and basophils, forms Charcot-Leyden crystals in eosinophilic diseases (such as asthma), and is a known disease marker, but CLCP2/LGALS10P1 does not share these properties[1][2][4]. Key clarification: You likely meant to refer to Charcot-Leyden crystal protein (galectin-10, LGALS10)—which is a disease marker and has defined diagnostic value—not its pseudogene (CLCP2/LGALS10P1). The pseudogene is not a therapeutic target, does not encode protein, and is not clinically actionable[1][4].

Other names

LGALS10P1Charcot-Leyden crystal protein pseudogene 2