Molecular Classification
Small Molecule
Disease Roles
Heavy metal poisoningIron overloadWilson's disease

Chelating Agents Overview

Chelating agents are molecules that bind to metal ions, forming stable ring-like complexes called chelates. This process alters the metal's chemical properties, enabling detoxification, removal of excess metals, or use in industrial processes. They are used in medicine to treat heavy metal poisoning and metal overload disorders. Industrial applications include water treatment, cleaning, and food preservation.

Mechanism of Action

Chelation: Formation of stable, soluble complexes with metal ions, facilitating their removal from the body or system.

Biological Functions

Metal ion binding
Detoxification

Disease Associations

Heavy metal poisoning
Iron overload
Wilson's disease

Safety Considerations

  • Depletion of essential metals (e.g., calcium, zinc)
  • Nephrotoxicity
  • Allergic reactions

Interacting Drugs

EDTA
DTPA
Penicillamine
Desferrioxamine B (DFO)
Dimercaprol (British anti-Lewisite)