Chemokine (C-C motif) receptor-like 2 pseudogene

Chemokine (C-C motif) receptor-like 2 pseudogene (ENSG00000255972) is a processed pseudogene, meaning it is a DNA sequence that arose from reverse transcription of mRNA from the functional CCRL2 gene and subsequent integration into the genome. Pseudogenes like this are nonfunctional segments of DNA that resemble genuine protein-coding genes, but due to disruptive mutations or lack of necessary regulatory elements, they do not produce functional proteins. They do not participate in normal cellular or disease processes, are not valid drug targets, and typically have no known biological or pharmacological significance[1][3][5][7]. This entry should not be considered a therapeutic target for drug discovery or development, in contrast to the functional gene CCRL2 (chemokine (C-C motif) receptor-like 2)[4][6]. Its status as a pseudogene is confirmed by GeneCards and genome annotation resources[7]. The functional gene CCRL2 is in the GPCR (G protein-coupled receptor) family and has some relevance in immune, inflammatory, and infection pathways, but the pseudogene does not encode any protein nor serve biological functions[6][3].

Other names

CCRL2 pseudogeneChemokine receptor-like 2 pseudogeneCCRL2P