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Chemotherapy
- Molecular classification
- Alkylating agents, Antimetabolites, Anti-microtubule agents, Topoisomerase inhibitors, Nitrosoureas, Corticosteroids
01
Overview
Chemotherapy refers to the use of cytotoxic drugs designed to destroy rapidly dividing cells. It is most commonly used for cancer treatment because cancer cells typically divide and grow much faster than normal body cells. Chemotherapy drugs work by interfering with cell division (mitosis), damaging DNA, or disrupting cellular machinery involved in replication and growth. Because chemotherapy targets all rapidly dividing cells—not just malignant ones—it often affects healthy tissues such as hair follicles, gastrointestinal lining, bone marrow, and skin.
- Other names
- Cytotoxic drugsAnticancer drugs
02
Mechanism of action
Cytotoxicity via disruption of mitosis/DNA damage/apoptosis
03
Biological functions
Cell death inductionInhibition of cell divisionDNA damageImmunogenic cell death
04
Disease associations
CancerBone marrow diseasesAutoimmune disorders
05
Safety considerations
Hair lossNauseaVomitingFatigueIncreased infection riskBone marrow suppression
06
Interacting drugs
Cyclophosphamide
8 more in the full profile.
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