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Target intelligence / Profile preview
Chikungunya Virus Capsid Protein (C)
- Target
- C
- Molecular classification
- Structural protein, Nucleocapsid protein
01
Overview
The capsid protein (C) of Chikungunya virus is a multifunctional, non-glycosylated nucleocapsid protein that plays several crucial roles in the viral life cycle. It forms the nucleocapsid that encapsulates the viral RNA genome, functions in virus assembly and budding, regulates viral replication, and acts as a pleiotropic regulator of both host and viral protein synthesis. It contains linear B cell epitopes, suggesting its importance in immune recognition.
02
Biological functions
Viral RNA encapsulationVirus assemblyVirus buddingRegulation of viral replicationRegulation of host and viral protein synthesisImmune recognition
03
Disease associations
InfectionChikungunya disease pathogenesis
04
Safety considerations
Potential for immune evasion through mutationsOff-target effects of capsid-targeting therapeutics
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