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Target intelligence / Profile preview
Chitinase A from *Serratia marcescens* (ChiA)
- Target
- ChiA
- Molecular classification
- Enzyme (Glycosyl hydrolase, Family 18)
01
Overview
Chitinase A (ChiA) from *Serratia marcescens* is an enzyme that catalyzes the random endo-hydrolysis of N-acetyl-beta-D-glucosaminide (1→4)-beta-linkages in chitin. It plays a crucial role in the degradation of chitin, a process essential for obtaining carbon and nitrogen sources from fungal cell walls and other chitin-containing materials. ChiA works synergistically with other chitinases like ChiB to break down chitin more efficiently[1][4][6].
- Other names
- Chitinase AChiA
02
Mechanism of action
Hydrolysis of N-acetyl-beta-D-glucosaminide (1→4)-beta-linkages in chitin
03
Biological functions
Chitin degradationcell wall disruption of fungi and other organismsnutrient acquisition
04
Disease associations
Antifungal rolespotential in biocontrol of fungal pathogens
05
Safety considerations
Generally considered safe due to its enzymatic nature
06
Interacting drugs
None specifically reported
07
Biomarkers
None specifically identified
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