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Chloride Ion (Cl⁻)
- Target
- Cl⁻
- Molecular classification
- Inorganic Anion, Electrolyte
01
Overview
The chloride ion is the anionic form of chlorine (Cl⁻) and is an essential electrolyte involved in maintaining fluid balance, nerve impulse transmission, and acid/base balance. While the ion itself isn't directly targeted by drugs, its transport mechanisms (chloride channels and transporters) are.
- Other names
- ChlorideCl-Cl(−1)
02
Mechanism of action
Drugs can target chloride channels to modulate ion flow. Some diuretics affect chloride reabsorption in the kidneys.
03
Biological functions
Maintains acid/base balanceTransmits nerve impulsesRegulates fluid movement into and out of cellsElectrolyte balance
04
Disease associations
Cystic fibrosis (related to chloride channel dysfunction)Epilepsy (related to chloride channel dysfunction)Hypertension (related to electrolyte imbalance)
05
Safety considerations
Electrolyte imbalanceHypochloremiaHyperchloremia
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