CHMP3 and RNF103 antisense RNA 1 (CHMP3-AS1)

CHMP3-AS1 is a human long non-coding RNA located on chromosome 2, transcribed as an antisense RNA overlapping the CHMP3 and RNF103 protein-coding genes[4][1]. Its classification as an "antisense RNA" means it can bind to the sense mRNA transcripts of these genes, potentially affecting their stability, splicing, or transcriptional regulation[3]. Like other long non-coding and antisense RNAs, its functions are primarily regulatory—modulating gene expression either in cis (locally) or in trans (distantly in the genome)[3]. As of current knowledge, CHMP3-AS1 itself has not been directly linked to specific diseases, described as a therapeutic target, or associated with pharmacological agents. There are no reported drugs or clinical biomarkers, nor any known notable safety concerns. Its biological role is likely similar to other antisense RNAs, which are increasingly understood to participate in fine-tuning gene regulation[3][4].

Other names

CHMP3-AS1

Not applicable (no drugs targeting CHMP3-AS1 reported)