Cholesterol Synthesis Pathway Enzymes ()

Cholesterol Synthesis Pathway Enzymes Overview

A collection of enzymes involved in the multi-step metabolic pathway that produces cholesterol. These enzymes catalyze sequential reactions, converting simple precursors into cholesterol, which is essential for cell membrane structure, steroid hormone synthesis, bile acid synthesis, and vitamin D synthesis. Key enzymes include HMG-CoA reductase, squalene synthase, and lanosterol synthase. Regulation of these enzymes, particularly HMG-CoA reductase, is crucial for maintaining cholesterol homeostasis.

Mechanism of Action

Inhibition of specific enzymes in the cholesterol synthesis pathway, such as HMG-CoA reductase

Biological Functions

Safety Considerations

Interacting Drugs