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Target intelligence / Profile preview
Chondrogenesis-associated transcript (CISTR)
- Target
- CISTR
- Molecular classification
- Long non-coding RNA (lncRNA)
01
Overview
Chondrogenesis-associated transcript (CISTR) is a long non-coding RNA gene located on chromosome 12 in humans. It has multiple splice variants and does not encode a protein. The transcript is implicated in the regulation of genes involved in chondrogenesis—cartilage cell differentiation and development—potentially acting through cis- and trans-chromosomal regulatory mechanisms. While it is recognized in annotation databases, its biological functions have not been fully characterized, and there is no evidence it is directly druggable or used as a biomarker in clinical settings.
- Other names
- CISTR-ACTCISTRACTre52431Chondrogenic regulator lncRNACis- and trans-chromosomal chondrogenic regulator transcript
02
Biological functions
Putative regulation of chondrogenesis (cartilage cell development and/or differentiation)Possible cis- and trans-chromosomal transcriptional regulation
03
Disease associations
Other
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