Target intelligence / Profile preview

Chromium (Cr)

Target
Cr
Molecular classification
Trace element, Mineral
01

Overview

Chromium is a transition metal and essential trace element primarily known for its role in regulating glucose metabolism. Trivalent chromium (Cr(III)) enhances insulin action by binding to chromodulin, potentially activating insulin receptors. While traditionally considered essential, its strict necessity is debated. Hexavalent chromium (Cr(VI)) is highly toxic. Dietary sources include brewer’s yeast, wheat germ, and kidney meats. Industrially, chromium is used in steel production, chrome plating, and as pigments.

Other names
Chromium (trace element)Cr
02

Mechanism of action

Binds to chromodulin, potentially activating insulin receptors and improving insulin sensitivity.

03

Biological functions

Glucose metabolism regulationInsulin action enhancementProtein metabolismCarbohydrate metabolismLipid metabolism
04

Disease associations

Diabetes (potential)Metabolic disorders (potential)
05

Safety considerations

Toxicity of hexavalent chromiumPotential toxicity from excessive trivalent chromium intake

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