Chromodomain Y-linked 14 pseudogene (CDY14P)

Chromodomain Y-linked 14 pseudogene (CDY14P) is an annotated human pseudogene located on the Y chromosome[1][5]. As a *pseudogene*, it resembles the functional chromodomain Y-linked genes (which are protein-coding and have roles in chromatin regulation and testis function), but CDY14P itself does not encode a functional protein[1][4][5]. Pseudogenes like CDY14P are defined as nonfunctional DNA segments bearing homology to active genes—they typically arise through gene duplication or retrotransposition, followed by mutational inactivation[4]. While most pseudogenes do not produce biologically active molecules, some can have regulatory effects on gene expression via RNA-based interactions in specific contexts; however, there is no evidence that CDY14P encodes regulatory RNAs or has a disease role or therapeutic relevance[2][4][5]. Key Points: - CDY14P is not a protein, receptor, enzyme, transporter, or other canonical drug target, but a pseudogene copy of a chromodomain Y-linked gene[1][4][5]. - There are no known drugs targeting this pseudogene, nor is there therapeutic or biomarker utility associated with it[1][5]. - The closest functional relatives, such as CDY1 and CDYL, are protein-coding and involved in chromatin modification and gene repression, often in male germ cells[3][8]. This does not apply to CDY14P due to loss of function. Clarification on accuracy: - The entry "chromodomain Y-linked 14 pseudogene" refers to a *nonfunctional* genetic element. It is not considered a drug target, nor is it a functional member of any major molecular family used in pharmacology or molecular biology. - Assigning target classifications, functional pathways, or clinical relevance is incorrect for CDY14P. Justification for is_target = false and is_incorrect = true: - CDY14P is a pseudogene[1][4][5]; pseudogenes, by definition, lack the ability to produce functional protein and are not considered actionable molecular targets. - There is nothing about "receptor" or active function in this locus. - No interacting molecules, disease links, or safety concerns are documented. In summary, "chromodomain Y-linked 14 pseudogene (CDY14P)" is a nonfunctional pseudogene in the human genome, not a targetable molecular entity.

Other names

chromodomain protein Y-linked 14 pseudogenechromodomain protein, Y-linked, 1 pseudogeneCDY14P