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Chromosome 1 open reading frame 105 (C1orf105)

Target: C1orf105
Molecular classification: Other (Protein of unknown function; classified in InterPro as DUF4548)

Overview

Chromosome 1 open reading frame 105 (C1orf105) is a protein-coding gene in humans with largely unknown function. It is classified as a \"protein of unknown function\" and includes a domain DUF4548. Little is known about its molecular role; it may be involved in general protein binding. There are some reported associations with rare diseases such as glycosylphosphatidylinositol biosynthesis defect 16 and nonimmune hydrops fetalis, but C1orf105 is not established as a disease gene nor as a therapeutic target. No drugs, biomarkers, or clear clinical roles are currently attributed to it[1][4][7][8].

Other names: C1orf105CA105

Biological functions

Unknown (may have \"protein binding\" activity, but specific functions are not established)

Disease associations

Glycosylphosphatidylinositol biosynthesis defect 16, Hydrops fetalis, nonimmune (possible associations, not established as a direct causal or driver gene)

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