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Chromosome 12 open reading frame 50 (C12orf50)
- Target
- C12orf50
- Molecular classification
- Other (uncharacterized protein with a CCCH-type zinc finger domain)
01
Overview
Chromosome 12 open reading frame 50 (C12orf50) is a human protein-coding gene located at chromosome 12q21.32, encoding a protein of approximately 47 kDa that contains a CCCH-type zinc finger domain near its N-terminus. The protein is predominantly expressed in the testis, with low expression in most other adult tissues. It is predicted to play a role in mRNA and protein binding, and has been implicated in the nuclear export of poly(A)+ mRNA. At the protein level, C12orf50 shows nuclear and cytoplasmic localization, is subject to various predicted post-translational modifications, and interacts (through experimental or predicted evidence) with proteins such as GAPDHS and GOLGA2. Its molecular function remains incompletely characterized, and it is not currently implicated in human disease or targeted by any therapeutic drugs.
- Other names
- C12orf50FLJ35821Uncharacterized protein C12orf50
02
Mechanism of action
None known
03
Biological functions
mRNA bindingProtein bindingInvolvement in poly(A)+ mRNA export from the nucleus
04
Disease associations
Other (no association with cancer, inflammation, neurodegeneration, infection, or cardiovascular disease reported as of current sources)
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