Chromosome 14 open reading frame 156 pseudogene (C14orf156 pseudogene)

Chromosome 14 open reading frame 156 pseudogene (C14orf156 pseudogene) is classified as a pseudogene, meaning it is a gene sequence that resembles a protein-coding gene but contains disabling mutations that prevent it from producing a functional protein.[1] Pseudogenes can arise through gene duplication or retrotransposition, usually resulting in sequences that are not transcribed or translated; however, some pseudogenes are transcribed into RNA and may act as regulators of protein-coding genes, for example, by generating small interfering RNAs or acting as decoys for microRNAs.[2][4] There is no clear evidence of protein coding capacity or direct therapeutic relevance for ENSG00000258542, and it is not commonly listed as a biomarker or drug target. This is not a therapeutic target—pseudogenes are generally not drug targets because they lack protein products and clear druggable function.[1][2][4] There is no indication this is a misspelling or incorrect entry. Some pseudogenes have regulatory roles, such as RNA decoys or microRNA sponges; the specific function of C14orf156 pseudogene is unknown and not described in major databases. The entry is found in Genecards, explicitly annotated as a pseudogene with no known protein function.[1] Pseudogenes may occasionally play regulatory roles at the RNA level, such as being sources of small interfering RNAs (siRNAs) or acting as competing endogenous RNAs (ceRNAs, or "sponges" for microRNAs), though this is not established for all pseudogenes and not shown for this entry.[2][4] Major curated resources do not list interacting drugs, mechanisms of action, biomarker status, or safety concerns for pseudogenes in general unless specifically implicated in disease biology.

Other names

C14orf156 pseudogene