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Chromosome 15 open reading frame 40 (C15orf40)
- Target
- C15orf40
- Molecular classification
- Other (protein of unknown function; classified as DUF167 by InterPro), Not receptor, enzyme, transporter, ion channel, transcription factor, or histone modification
01
Overview
Chromosome 15 open reading frame 40 (C15orf40) is a mammalian protein of 153 amino acids, encoded by the C15orf40 gene on chromosome 15, with no well-characterized molecular function[2][4][6]. It is classified as a protein of unknown function (DUF167 via InterPro), and while it is ubiquitously present in various tissues, there are no direct experimental data on its mechanism of action, protein partners, or cellular roles[5][6]. Published functional analyses have not identified any canonical target-like activity such as enzymatic, receptor, or ion channel function; reported disease associations are limited and do not support a confirmed biological or pathogenic role[3][7]. As such, C15orf40 remains a poorly understood gene product lacking evidence for therapeutic targeting or biomarker application, and is not considered a receptor, enzyme, transporter, or classified target under current guidelines[3][5][7][6].
- Other names
- UPF0235 protein C15orf40MGC29937CO040_HUMANC15orf40
02
Mechanism of action
None known (no drugs or compounds target this molecule directly; mechanism not established)
03
Biological functions
Unknown (no established roles such as signal transduction, apoptosis, cell cycle, etc.; predicted roles are not yet confirmed)Potential involvement in protein complexes and mitochondrial processes (speculative, not well-characterized)
04
Disease associations
Other (not definitively linked to diseases; found within a microdeletion associated with premature ovarian failure, but no direct functional role established)Possible association with failure of tooth eruption, primary (not clear if causative)No clear associations with cancer, inflammation, neurodegenerative disease, cardiovascular disease, or infection
05
Safety considerations
None known (no safety or therapeutic challenges identified)
06
Interacting drugs
None known (no established interactions with therapeutic drugs or experimental compounds)
07
Biomarkers
None known (not used as a biomarker for patient selection or efficacy monitoring)
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