Chromosome 17 open reading frame 113 (C17orf113)

Chromosome 17 open reading frame 113 (C17orf113) is a human protein of the DUF866 family, a group whose members are found exclusively in eukaryotes and remain largely uncharacterized. C17orf113 contains an internal two-fold symmetry and a zinc-binding domain, features that hint at a conserved structural and potential regulatory role. Experimental evidence indicates possible involvement in mitochondrial oxidative phosphorylation, likely linked to maintaining mitochondrial membrane structure and integrity, but its precise molecular function, biological partners, and disease associations are currently unknown. There are no established drugs, disease links, or biomarker roles for this protein, and it is not presently recognized as a therapeutic target. C17orf113 currently lacks functional and clinical characterization and is not listed as a known target in pharmacology or therapeutic applications. The only molecular family clearly associated is as a "DUF866 domain-containing protein" (DUF: Domain of Unknown Function), generally classed as "Other." There is no evidence that C17orf113 is a "transmembrane protein" despite some alternative naming; the structure does not confirm a typical transmembrane domain. No known disease associations, drug interactions, or biomarker functions are reported in the experimental or biomedical literature.

Other names

C17orf113Uncharacterized protein C17orf113transmembrane protein C17orf113