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Chromosome 17 open reading frame 89 pseudogene

Molecular classification
Other (Pseudogene)
01

Overview

Chromosome 17 open reading frame 89 pseudogene (ENSG00000270598) is an annotated pseudogene on human chromosome 17. Pseudogenes are genomic sequences that resemble functional genes but are rendered nonfunctional through disabling mutations such as frameshifts, premature stop codons, or lack of regulatory elements required for coding gene expression. While pseudogenes as a class can occasionally participate in regulatory networks (for example, by acting as competitive endogenous RNAs or influencing the expression of functional parental genes), most—including this locus—are not currently attributed with regulatory or protein-coding functions. There is no evidence that chromosome 17 open reading frame 89 pseudogene encodes a protein, participates in significant biological pathways, or plays a role in disease. There are no drugs or therapies targeting this pseudogene, and it is not used as a biomarker for patient selection or disease monitoring

Other names
ENSG00000270598C17orf89P
02

Biological functions

There is no established function for this pseudogene. Most pseudogenes, including this one, are considered nonfunctional, although some pseudogenes have been implicated in regulation through RNA-based mechanisms in rare cases. No specific function is documented for this entry
03

Disease associations

None known specifically for this pseudogene. While certain pseudogenes are broadly associated with cancer or other disease states, there is no evidence or literature support for a disease role for chromosome 17 open reading frame 89 pseudogene

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