Chromosome 17 open reading frame 98 pseudogene (ENSG00000260674)

Chromosome 17 open reading frame 98 pseudogene (ENSG00000260674) is classified as a human pseudogene located on chromosome 17. Pseudogenes are genomic DNA sequences similar to normal genes but are nonfunctional; they may arise via gene duplication (unprocessed/duplicated pseudogenes), retrotransposition of mRNA (processed pseudogenes), or single-copy gene mutation (unitary pseudogenes)[1][2]. Most pseudogenes lack functional protein-coding capacity due to disabling mutations such as frameshifts or premature stop codons, or are missing promoters necessary for gene expression[1][2][3]. While a small fraction of pseudogenes may be transcribed and have regulatory functions—such as acting as competing endogenous RNAs or influencing nearby gene expression—the vast majority, including chromosome 17 open reading frame 98 pseudogene, lack evidence for functional RNA or protein products[1][3][5]. This locus is not recognized as a therapeutic target, does not encode a receptor, enzyme, or other druggable molecular entity, and is not associated with known disease biology or targeted by drugs. Its name, annotation as a "pseudogene," and lack of any reported functional or translational impact indicate that it is not meaningful for drug targeting or biomarker development[1][2][5].

Other names

C17orf98PC17orf98 pseudogenechromosome 17 open reading frame 98 (pseudogene)