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Chromosome 18 open reading frame 32 pseudogene (C18orf32 pseudogene)

Target
C18orf32 pseudogene
Molecular classification
Other (pseudogene)
01

Overview

This entry refers to a pseudogene—a nonfunctional segment of DNA located on chromosome 18 that shows sequence similarity to the protein-coding C18orf32 gene. Pseudogenes are segments of DNA that arise through duplication or mutation of functional genes and do not produce active protein products. The existence of this pseudogene does not imply biological function, disease association, or druggability. The Ensembl gene identifier provided (ENSG00000270782) may represent a computationally annotated or uncharacterized pseudogene, but it does not denote a recognized therapeutic target. Pseudogenes can affect genomic studies through sequence similarity to functional genes.

Other names
C18orf32 pseudogene
02

Safety considerations

Not direct therapeutic targets; however, pseudogenes are known to complicate genetic studies (PCR amplification bias, misannotation, etc.).

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