Target intelligence / Profile preview

Chromosome 18 open reading frame 54 (C18orf54)

Target
C18orf54
Molecular classification
Other
01

Overview

Chromosome 18 open reading frame 54 (C18orf54), also known as lung adenoma susceptibility protein 2 (LAS2), is a protein-coding gene in humans located on chromosome 18.[3][5][7] This protein is suggested to negatively regulate cell population proliferation and may play a role in tumor suppression, with a noted association with lung adenoma.[3][7] There is limited functional or mechanistic data, and it is not classified as a receptor, enzyme, transporter, or established therapeutic target. No drug interactions, clinical biomarkers, or notable safety concerns are reported in current resources.[3][5][7]

Other names
Lung adenoma susceptibility protein 2LAS2MGC33382
02

Biological functions

Negative regulation of cell population proliferationPossible role in cell proliferation
03

Disease associations

Cancer (specifically association with lung adenoma)

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