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Target intelligence / Profile preview
Chromosome 19 open reading frame 53 (C19orf53)
- Target
- C19orf53
- Molecular classification
- Other (Uncharacterized protein family UPF0390)
01
Overview
Chromosome 19 open reading frame 53 (C19orf53) encodes a protein known as Leydig cell tumor 10 kDa protein homolog, with 99 amino acids. It is classified as part of an uncharacterized protein family (UPF0390), and its function is largely unknown. Preliminary evidence suggests it may play a role in the development of hypercalcemia of malignancy, particularly in Leydig cell tumors. As of now, there are no known drug interactions, established mechanisms of action, or validated biomarker roles. The gene is listed in major genetic databases (HGNC:24991, NCBI Gene:28974, UniProt: Q9UNZ5) but is not currently categorized as a therapeutic target such as a receptor, enzyme, transporter, or similar protein family. There are no notable safety concerns or therapeutic challenges reported, primarily due to its uncharacterized role in disease.
- Other names
- Leydig cell tumor 10 kDa protein homologL10KHero11HSPC023LYDG10
02
Biological functions
Protein of unknown functionsuggested possible role in hypercalcemia of malignancy
03
Disease associations
Cancer (Leydig cell tumor)possible association with hypercalcemia of malignancy
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