Chromosome 2 open reading frame 14 pseudogene (C2orf14 pseudogene)

Chromosome 2 open reading frame 14 pseudogene (C2orf14 pseudogene, ENSG00000254145) is a processed pseudogene located on human chromosome 2. Processed pseudogenes are DNA sequences that resemble functional genes but have lost their coding potential, typically as a result of retrotransposition of mRNA and integration into the genome without regulatory elements. As such, this pseudogene does not produce a functional protein product, nor is it involved in any known therapeutic mechanism or disease pathway. While pseudogenes can occasionally be transcribed and participate in post-transcriptional regulation (e.g., acting as microRNA decoys or sources of regulatory RNA), there is no evidence for any such function for ENSG00000254145 specifically. It is primarily considered a molecular relic with no current functional annotation[2][4][5][1]. Key facts: - This is not a functional gene, receptor, enzyme, or other druggable target. - The term "open reading frame" in its name refers to sequence homology, not to any confirmed or predicted protein product. - Its status as a pseudogene reflects its lack of protein-coding capability and lack of therapeutic relevance[2][4][1].

Other names

C2orf14 pseudogeneENSG00000254145