Chromosome 2 open reading frame 69 pseudogene 4 (C2orf69P4)

C2orf69P4 is a human processed pseudogene located on chromosome 2, named as the fourth pseudogene related to the C2orf69 locus[3]. Pseudogenes are generally nonfunctional, transcriptionally inactive DNA segments derived from once-functional genes, often acquiring mutations that prevent them from encoding active proteins[4][5]. C2orf69P4 is distinguished from the functional C2orf69 gene, which encodes a mitochondrial protein involved in mitochondrial respiratory chain function and has been linked to certain rare genetic diseases with autoinflammation and neurodevelopmental features[1]. However, C2orf69P4 itself lacks coding potential and is not implicated in molecular pathways or as a therapeutic target[3][5]. C2orf69P4 is not an active or therapeutically relevant target. It is a non-coding pseudogene and should not be considered in structured drug target datasets. The functional gene of interest would be C2orf69, not its pseudogene (C2orf69P4)[1][3][5].

Other names

C2orf69P4Chromosome 2 open reading frame 69 pseudogene 4

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