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Chromosome 20 open reading frame 173 (C20orf173) is an uncharacterized human protein encoded by the C20orf173 gene, located on chromosome 20. It is a predicted protein with a C-terminal coiled-coil region and has been annotated to possess potential beta-galactoside (CMP) alpha-2,3-sialyltransferase activity, suggesting a possible role in sialylation and the biosynthesis of gangliosides via lactosylceramide, as well as involvement in protein glycosylation[3][10][5]. It is currently not functionally well-characterized in terms of involvement in disease or as a drug target and has no known therapeutically relevant interacting drugs or established biomarker roles[3][10][2]. No specific pathways or disease mechanisms have been conclusively associated with this protein, and it is not classified under major therapeutic target classes such as receptor, enzyme, transporter, or transcription factor[3][10][7].
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