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Chromosome 20 open reading frame 30 pseudogene

Molecular classification
Pseudogene, Non-coding RNA
01

Overview

Chromosome 20 open reading frame 30 pseudogene is a non-coding genomic sequence on human chromosome 20 that shares homology with a putative protein-coding gene but is unable to produce a functional protein product due to disabling mutations or loss of regulatory elements. Pseudogenes like this may play minor regulatory roles at the RNA level, such as acting as competing endogenous RNAs or serving as sources of small regulatory RNAs, although most are functionless DNA remnants and not subjects of therapeutic targeting. The existence of the pseudogene is a result of gene duplication, retrotransposition, or other genomic events, and it is annotated according to systematic genomic conventions for open reading frames and pseudogenes[1][2][4][6].

Other names
ENSG00000238165C20orf30P
02

Biological functions

May have gene expression regulatory roles at the RNA level, e.g., as noncoding RNA, microRNA decoy, or antisense RNA regulatorprimarily considered a non-functional gene remnant
03

Disease associations

Other (some pseudogenes may play regulatory roles in cancer, but no evidence directly links this specific pseudogene to disease)

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