Chromosome 20 open reading frame 69 pseudogene (C20orf69 pseudogene)

Chromosome 20 open reading frame 69 pseudogene (C20orf69 pseudogene, ENSG00000226838) is annotated as a pseudogene on human chromosome 20. Pseudogenes are defined as genomic sequences similar to functional genes but incapable of encoding a functional protein—typically due to frameshifts, truncations, or disabling mutations. While long considered “junk DNA,” some pseudogenes have been shown to regulate gene expression through RNA-mediated mechanisms, such as acting as microRNA sponges or generating regulatory small RNAs, though such functions are context- and locus-specific and not established for C20orf69 pseudogene itself. There is no evidence that C20orf69 pseudogene encodes a functional protein, serves as a therapeutic target, or participates directly in human disease. It is included in reference genomics databases for completeness of genomic annotation and evolutionary studies.

Other names

Chromosome 20 ORF69 pseudogeneC20orf69 pseudogene