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Chromosome 3 open reading frame 38 pseudogene (C3orf38P (pseudogene abbreviations often use parent symbol + “P”, but may vary in literature; no standardized abbreviation is widely established for this entity)[4])
- Target
- C3orf38P (pseudogene abbreviations often use parent symbol + “P”, but may vary in literature; no standardized abbreviation is widely established for this entity)[4]
- Molecular classification
- Pseudogene, Noncoding RNA (may be transcribed as noncoding RNA)
01
Overview
Chromosome 3 open reading frame 38 pseudogene (ENSG00000230485) is a **pseudogene** related to the protein-coding C3orf38 gene. Pseudogenes are genomic DNA sequences similar to normal genes but are typically nonfunctional due to disabling mutations or lack of regulatory elements. However, some pseudogenes can be transcribed and may play roles in gene regulation, such as acting as microRNA decoys or producing siRNAs, with implications in cancer and cellular regulation[2][3]. There is no evidence that this pseudogene encodes a functional protein or serves as a direct target for drugs. Identifiers and reported genomic coordinates confirm it is a distinct noncoding element related to, but not the same as, the protein-coding C3orf38 gene[4][1].
- Other names
- C3orf38 pseudogeneChromosome 3 open reading frame 38 pseudogeneENSG00000230485LOC285237 (pseudogene context)[4]
02
Mechanism of action
null
03
Biological functions
Possible regulation of gene expression by acting as a microRNA decoy or being processed into small interfering RNAs (as described for some pseudogenes, but not specifically annotated for this pseudogene)[2][3]No known direct protein-coding function
04
Disease associations
Other (general role of pseudogenes in gene regulation and possible association with alterations in diseases such as cancer via regulatory RNAs; no direct evidence for this specific pseudogene)[2][3]
Beyond the preview
Go deeper on Chromosome 3 open reading frame 38 pseudogene (C3orf38P (pseudogene abbreviations often use parent symbol + “P”, but may vary in literature; no standardized abbreviation is widely established for this entity)[4]).
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