Chromosome 4 open reading frame 46 pseudogene (ENSG00000270655)

Chromosome 4 open reading frame 46 pseudogene (ENSG00000270655) is a DNA sequence on human chromosome 4 that is classified as a pseudogene. Pseudogenes are genomic sequences similar to normal genes but that have lost their ability to encode proteins or functional RNAs, typically due to mutations such as premature stop codons or frameshifts. Most pseudogenes, including this one, are biologically inert and do not have direct roles in cell signaling, metabolism, or disease unless exceptions are specifically described. Pseudogenes can sometimes create challenges in genetic studies and assays due to sequence similarity with their functional parent genes, but the overwhelming consensus is that "chromosome 4 open reading frame 46 pseudogene" has no known function, druggability, or disease association. The term "open reading frame" in its name only refers to sequence homology; as a pseudogene, this locus does not encode an active protein product. Some pseudogenes have regulatory or disease-modifying roles, but as of current evidence and common biological knowledge, ENSG00000270655 is not reported to have such functions. If you are seeking conventional therapeutic targets (receptors, enzymes, etc.), this gene is not regarded as one and is sometimes a source of confusion in automated gene annotation efforts.

Other names

C4orf46 pseudogeneENSG00000270655

Not applicable