Chromosome 5 open reading frame 43 pseudogene

Chromosome 5 open reading frame 43 pseudogene (ENSG00000264246) is a genomic DNA segment on human chromosome 5 that resembles a functional gene (open reading frame 43) but contains mutations or truncations that prevent it from producing a functional protein product[2][4]. Pseudogenes can arise by duplication of functional genes (unprocessed pseudogene) or by reverse transcription and reinsertion of mRNA (processed pseudogene), generally lacking biological activity[1][4]. While most pseudogenes like this one serve no direct biological role, some can rarely regulate gene networks through competing endogenous RNA or serve as evolutionary markers[1]. However, there is no evidence that "chromosome 5 open reading frame 43 pseudogene" has any such function, clinical interest, or therapeutic relevance.

Other names

C5orf43PENSG00000264246