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Chromosome 5 open reading frame 60 pseudogene

Molecular classification
Other (Pseudogene)
01

Overview

Chromosome 5 open reading frame 60 pseudogene (ENSG00000228259) is a **pseudogene**, meaning it is a segment of DNA that resembles a gene but is typically nonfunctional; it does not produce a functional protein product[2][4]. Pseudogenes arise through duplication or retrotransposition of protein-coding genes, after which they accumulate disabling mutations and lose their protein-coding ability[4]. While many pseudogenes are transcriptionally silent, a subset can be transcribed and may exert regulatory effects, for example by acting as competing endogenous RNAs or sources of regulatory peptides, but such functions are relatively rare and mostly unexplored[1][3][4]. Chromosome 5 open reading frame 60 pseudogene is **not considered a drug target**, nor is it a member of any receptor, enzyme, transporter, or other canonical molecular family used in therapeutics.

Other names
ENSG00000228259
02

Biological functions

Other (pseudogenes are mostly non-functional, though emerging evidence shows some may regulate gene expression or have rare regulatory RNA functions)
03

Disease associations

Other (some pseudogenes carry disease-associated SNPs and have been implicated in transcriptome perturbation in cancer and organ development, but most have no direct disease role)

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