Target intelligence / Profile preview

Chromosome 6 open reading frame 132 (C6orf132)

Target
C6orf132
Molecular classification
Other, Long noncoding RNA (lncRNA)
01

Overview

Chromosome 6 open reading frame 132 (C6orf132) is an uncharacterized gene that encodes a predicted long noncoding RNA (lncRNA) also referred to as LncCCLM or "cervical cancer lymphatic metastasis-associated lncRNA." Recent research indicates that altered expression of C6orf132 may be associated with lymphatic metastasis and poor prognosis in cervical cancer patients, suggesting a role in cancer progression[5][8][9]. Its specific molecular function and mechanism remain uncharacterized; there are no established therapeutic drugs known to target it, nor has it been validated as a classical therapeutic target (e.g., receptor, enzyme, transporter, etc.)[9]. While its utility is currently limited to biomarker research, further studies are required to elucidate its biological and therapeutic relevance.

Other names
C6orf132bA7K24.2LncCCLMCervical cancer lymphatic metastasis-associated lncRNAUncharacterized protein C6orf132
02

Biological functions

Possible involvement in regulation related to lymphatic metastasis in cervical cancer
03

Disease associations

Cancer (specifically, cervical cancer and lymphatic metastasis association)
04

Biomarkers

Potential biomarker for lymph node metastasis in cervical cancer[8]

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