Chromosome 6 open reading frame 52 (C6orf52)

Chromosome 6 open reading frame 52 (C6orf52) encodes a putative, uncharacterized protein in humans and is classified as a protein-coding gene. Bioinformatics predictions suggest it is involved in tRNA binding activity and selenocysteine incorporation, with nuclear localization, but no direct evidence exists for these functions in humans. The gene has been implicated by association with retinitis pigmentosa 25, but no mechanistic role or validated disease pathway has been established. In model organisms (cattle), C6orf52-related loci produce non-coding RNA variants linked to metabolic traits, but this significance is not firmly demonstrated in humans. No drugs, targeted therapies, or biomarker uses have been established for C6orf52. C6orf52 remains a poorly characterized gene without established biological function or therapeutic targeting. It is not currently recognized as an enzyme, receptor, transporter, or other canonical drug target class. No known safety concerns or clinical roles are reported in the scientific literature.

Other names

C6orf52putative uncharacterized protein C6orf52CF052_HUMAN