Chromosome 9 open reading frame 57 (C9orf57)

Chromosome 9 open reading frame 57 (C9orf57) is a protein-coding gene that encodes a small (approximately 14 kDa) uncharacterized protein. C9orf57 has been observed to show nuclear localization in testicular tissues, particularly in the context of germ cell development or differentiation, suggesting a possible (but unconfirmed) role in spermatogenesis. Its specific biological functions remain poorly defined and it is not currently considered a canonical therapeutic target such as a receptor, enzyme, or transporter. There are no known drugs that interact with C9orf57, no established roles in major common disease pathways such as cancer or neurodegeneration, and no validated utility as a biomarker or safety concern. Diseases genetically associated with C9orf57 include some forms of autosomal recessive deafness, but mechanistic details are lacking. Alternative names and database identifiers for this gene and protein are numerous, most commonly C9orf57 and "uncharacterized protein C9orf57".

Other names

Uncharacterized protein C9orf57RP11-346E17.3CI057GC09M070123GC09M070113GC09M071895GC09M073856GC09M074666GC09M044488