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Target intelligence / Profile preview
Cilia- and flagella- associated protein 210 (CFAP210)
- Target
- CFAP210
- Molecular classification
- Other
01
Overview
Cilia- and flagella- associated protein 210 (CFAP210) is a microtubule inner protein (MIP) located in the axoneme of motile cilia and flagella, specifically forming part of the dynein-decorated doublet microtubules (DMTs). This protein is essential for the structure and function of motile cilia, required for their beating, and contributes to flagellated sperm motility. CFAP210 is a structural protein, not classically categorized as a receptor, enzyme, or ion channel. There is currently no evidence that CFAP210 is a therapeutic target, nor have drugs been developed to modulate its function. The gene is referenced in large genetic screens and disease association databases but is not a focus for biomarker usage, drug interaction, or safety profile in current clinical or translational research.
- Other names
- CFAP210C2orf77CCDC173LOC129881Coiled-coil domain-containing protein 173hypothetical LOC129881protein CFAP210cilia- and flagella-associated protein 210coiled-coil domain containing 173
02
Biological functions
Motile cilia beatingSperm motility (flagellated sperm movement)Axonemal microtubule structure (component of doublet microtubules)
03
Disease associations
Other
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