Target intelligence / Profile preview

Cilia- and flagella-associated protein 144 (CFAP144)

Target
CFAP144
Molecular classification
Other
01

Overview

Cilia- and flagella-associated protein 144 (CFAP144) is a microtubule-binding protein found in the axonemal microtubules of cilia, where it likely contributes to the structure and function of motile cilia, such as those required for sperm motility[2][3][6][9]. The protein is predicted to be involved specifically in the movement of flagellated sperm and is categorized as a member of the FAM183 family. No evidence supports its current use as a direct therapeutic target, nor are there drugs reported to interact with CFAP144[2][3][6]. Clinical associations include a possible link to autism spectrum disorder, although supporting evidence is limited and not well established[3].

Other names
FAM183ALOC440585hCG23177Protein FAM183Afamily with sequence similarity 183 member A
02

Biological functions

Microtubule bindingFlagellated sperm motility
03

Disease associations

Autism spectrum disorderOther (limited evidence)

Beyond the preview

Go deeper on Cilia- and flagella-associated protein 144 (CFAP144).

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Drug pipeline

Full profile access

Explore the programs pursuing this target and their development progress.

  • Drug candidates
  • Developers
  • Development stage

Clinical trials

Full profile access

Follow the clinical studies evaluating therapies directed at this target.

  • Trial design
  • Status
  • Readouts

Competitive landscape

Full profile access

Compare approaches across drug candidates, modalities, and indications.

  • Programs
  • Modalities
  • Indications

Literature & evidence

Full profile access

Investigate the research and source evidence behind target biology and development.

  • Publications
  • Sources
  • Analysis

Patents

Full profile access

Explore patent activity around therapies and technologies addressing this target.

  • Patents
  • Assignees
  • Technologies

Research & analysis

Full profile access

Connect target biology, drug development, and emerging evidence in your research.

  • Biology
  • Development news
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on Cilia- and flagella-associated protein 144 (CFAP144).

Explore the full profile

Gosset Free

Get started with Gosset.

Enter your work email and we’ll be in touch with next steps.

Work email preferred.

Book a call