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Cilia- and flagella-associated protein 144 (CFAP144) is a microtubule-binding protein found in the axonemal microtubules of cilia, where it likely contributes to the structure and function of motile cilia, such as those required for sperm motility[2][3][6][9]. The protein is predicted to be involved specifically in the movement of flagellated sperm and is categorized as a member of the FAM183 family. No evidence supports its current use as a direct therapeutic target, nor are there drugs reported to interact with CFAP144[2][3][6]. Clinical associations include a possible link to autism spectrum disorder, although supporting evidence is limited and not well established[3].
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