Cilia and flagella associated protein 97 domain-containing 2 (CFAP97D2)

Cilia and flagella associated protein 97 domain-containing 2 (CFAP97D2) is a protein in humans encoded by the CFAP97D2 gene, located on chromosome 13q34[1]. This gene belongs to the CFAP97 family, with three members (CFAP97, CFAP97D1, and CFAP97D2), and is conserved across a wide range of vertebrates[1]. The protein exists in several isoforms ranging from approximately 98 to 166 amino acids, exhibiting a nuclear leucine zipper motif and a predicted nuclear localization signal[1]. Although its precise molecular and biological functions remain uncharacterized, bioinformatic evidence points to a potential role in cytoskeletal regulation associated with cilia and flagella, suggesting involvement in processes such as spermatogenesis and maintenance of cellular structural integrity[1][3][4]. There are currently no known drug interactions, described mechanism of action, or established role as a biomarker or therapeutic target. No notable safety or therapeutic concerns are reported, reflecting the uncharacterized and non-druggable status of this protein as of present knowledge[1][4].

Other names

CFAP97D2Uncharacterized protein CFAP97D2CFAP97 domain-containing protein 2C17orf105 homologCFA97_HUMANKIAA1430HMW