Ciprofloxacin

Ciprofloxacin is a **second-generation fluoroquinolone antibiotic** used to treat a wide range of bacterial infections in humans[3][1]. Its chemical name is 1-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid, with a molecular formula C₁₇H₁₈FN₃O₃ and a molecular weight of about 331.3 g/mol[1][5]. Ciprofloxacin acts by inhibiting bacterial enzymes DNA gyrase (topoisomerase II) and topoisomerase IV, which are essential for bacterial DNA replication, repair, and transcription, leading to bacterial cell death[2][3][4][6][8]. It is active against a variety of Gram-negative and some Gram-positive bacteria, but it is not itself a molecular target[2][4][6]. Safety concerns include the potential for tendon rupture, peripheral neuropathy, central nervous system effects (such as seizures), QT prolongation, and serious hypersensitivity reactions, thus limiting its use to cases without safer or effective alternatives[4][6]. The drug is widely used under multiple brand names and is formulated for oral, intravenous, and topical administration[3][1].\n\nIn summary, "Ciprofloxacin" is a drug, not a biological target such as a receptor, enzyme, or transporter. The true targets of ciprofloxacin are the bacterial enzymes **DNA gyrase (topoisomerase II)** and **topoisomerase IV**. For structured target information, you should query for these enzyme names directly, not the drug itself[2][4].

Other names

CiprofloxacineCiprofloxacinoCiprobayBAY Q 3939CIPROCiproxinCiproCiprofloxacinum