Target intelligence / Profile preview

CIR1 pseudogene 1 (CIR1P1)

Target
CIR1P1
Molecular classification
Other (Pseudogene)
01

Overview

CIR1 pseudogene 1 (CIR1P1) is a pseudogene in humans associated with the parental CIR1 gene, which encodes "corepressor interacting with RBPJ 1," a protein involved in transcriptional regulation and repression via the Notch signaling pathway[11][5]. Unlike its protein-coding counterpart, CIR1P1 does not produce a functional protein. Pseudogenes such as CIR1P1 may sometimes have regulatory or evolutionary functions, including potential competition for microRNA binding or ceRNA (competing endogenous RNA) effects, but there is no experimental evidence for CIR1P1 having a specific biological function, disease link, or utility as a drug target at this time[3][7][11].

Other names
CIR1P1corepressor interacting with RBPJ, 1 pseudogene 1CIR1 pseudogene 1
02

Mechanism of action

none; there are no drugs targeting CIR1P1 as it does not encode a receptor or enzyme

03

Biological functions

There is no direct protein function; however, pseudogenes may regulate gene expression through mechanisms such as competition for miRNAs and involvement in ceRNA networksCIR1P1’s specific ceRNA/regulatory role is not established.
04

Disease associations

Currently, there are no directly attributed disease roles for CIR1P1more broadly, pseudogene expression can relate to cancer and other diseases via regulation of their functional paralogsno evidence links CIR1P1 specifically

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