CKAP2 divergent transcript (CKAP2-DT)

CKAP2 divergent transcript (CKAP2-DT) is a long non-coding RNA (lncRNA) gene located near the CKAP2 locus on human chromosome 13. Divergent transcripts are a class of lncRNAs transcribed in the opposite direction from nearby protein-coding genes within a short genomic distance (typically within 300-500 base pairs). The specific biological role and disease association of CKAP2-DT have not been thoroughly characterized in publicly available literature; it is primarily annotated as a genomic feature without clear evidence as a therapeutic target or established biomarker. This distinguishes it from the protein-coding gene CKAP2 (cytoskeleton associated protein 2), which is involved in microtubule stabilization, cell division, and has been studied as a biomarker and mechanistic contributor to several diseases, including cancer and rheumatoid arthritis. If you are seeking information on the protein-coding gene CKAP2, it is a distinct entity from CKAP2-DT. CKAP2-DT as a divergent transcript does not code for a protein and does not currently meet criteria for a druggable therapeutic target.

Other names

CKAP2-DTENSG00000278238123706541