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CKLF-like MARVEL transmembrane domain containing 7 pseudogene
- Molecular classification
- Pseudogene
01
Overview
CKLF-like MARVEL transmembrane domain containing 7 pseudogene (ENSG00000227371) is a nonfunctional DNA sequence in the human genome, homologous to the protein-coding CMTM7 gene. Pseudogenes arise from gene duplication, retrotransposition, or mutation events causing loss of function, and are unable to produce functional protein products due to disabling mutations (such as insertions, deletions, frameshifts, or lack of regulatory sequences). Although some pseudogenes have regulatory roles, CKLF-like MARVEL transmembrane domain containing 7 pseudogene has not been implicated as a drug target and is not recognized for any functional role in human disease or therapy.
- Other names
- AC074085.1CKLF-like MARVEL transmembrane domain containing 7 (CMTM7) pseudogene
02
Biological functions
Pseudogene sequences are typically nonfunctional copies of genes, lacking protein-coding abilitySome pseudogenes have been shown to play regulatory roles (e.g., RNA interference), but there is no evidence for this specific pseudogene
03
Disease associations
None known for ENSG00000227371 itself (some pseudogenes have regulatory roles in diseases, but this is not reported for this entry)
04
Safety considerations
no safety or therapeutic challenges, as pseudogenes are not drug targets
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