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Target intelligence / Profile preview
CKMT2 antisense RNA 1 (CKMT2-AS1)
- Target
- CKMT2-AS1
- Molecular classification
- Long non-coding RNA (lncRNA), Antisense RNA
01
Overview
CKMT2 antisense RNA 1 (CKMT2-AS1) is a long non-coding RNA gene that acts in an antisense fashion and is involved in transcriptional regulation. Located on chromosome 5, this lncRNA is classified as an antisense RNA due to its overlap with the CKMT2 protein-coding gene locus. CKMT2-AS1 is expressed in multiple transcript variants and is associated with cancer, particularly colorectal cancer, through its regulatory roles. Unlike CKMT2, which encodes the mitochondrial creatine kinase 2 enzyme, CKMT2-AS1 is a non-coding RNA and is not a molecular target for drugs or direct therapeutic interventions. The available data support involvement of CKMT2-AS1 in cell regulation processes often dysregulated in cancer, though further functional and mechanistic studies are warranted.
- Other names
- CTC-281B15.1CKMT2-AS1
02
Mechanism of action
not applicable, as CKMT2-AS1 is not a direct drug target.
03
Biological functions
Transcriptional regulation via antisense activityPotential involvement in cell proliferation and apoptosis regulation (inferred from association with cancer)
04
Disease associations
CancerColorectal cancer
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