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Class-wide: specific receptors, enzymes, and protein-protein interfaces

Molecular classification
Receptor, Enzyme, Protein-protein interface
01

Overview

The term 'Class-wide: specific receptors, enzymes, and protein-protein interfaces' is a high-level classification used to group various types of biological molecules that serve as drug targets. It is not a single protein or gene but a descriptive category found in pharmacological ontologies and databases like the IUPHAR/BPS Guide to PHARMACOLOGY (Alexander et al., 2023). This category includes diverse functional groups such as G protein-coupled receptors, catalytic enzymes, and the physical interfaces where two or more proteins interact to transmit signals. Because it is a broad grouping, it lacks a specific biological function or a direct role in a single disease state. Instead, it serves as an organizational framework for specific, actionable targets that are the focus of drug development and clinical research. Consequently, there are no drugs that target this 'class' as a whole, nor are there specific biomarkers or safety concerns associated with the category itself.

02

Mechanism of action

Not applicable as this is a broad classification category.

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